MS159 is a potent nuclear receptor binding SET structural domain protein 2 ( NSD2 ) PROTAC degrader. MS159 inhibits the growth of tumour cells. MS159 is a useful chemical tool for exploring the role of NSD2 in health and disease. Appearance:Solid In Vitro:MS159 (0.5-10 μM, 48 h) can induce the degradation of NSD2 protein in a time- and dose-dependent manner while the induced NSD2 degradation is reversible in 293FT cells. MS159 (2.5 μM, 72 h) can effectively degrade NSD2 as well as IKZF1 and IKZF3 in m Biological Activity:MS159 is a potent nuclear receptor binding SET structural domain protein 2 ( NSD2 ) PROTAC degrader. MS159 inhibits the growth of tumour cells. MS159 is a useful chemical tool for exploring the role of NSD2 in health and disease.
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MS159
CAS number：unknown molecular formula：C43H40N8O10
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C43H40N8O10 |
| molecular weight | 828.83 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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MSDS
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