CAS number：444722-95-6 molecular formula：C18H22N6O3S
NU6102 是一种有效的 CDK1 和 CDK2 抑制剂，对 CDK1/cyclinB 和 CDK2/cyclinA3 的 IC50 分别为 9.5 nM 和 5.4 nM。NU6102 对 CDK1/CDK2 的选择性比对 CDK4 (IC50 为 1.6 μM)，DYRK1A (IC50 为 0.9 μM)，PDK1 (IC50 为 0.8 μM) 和 ROCKII (IC50 为 0.6 μM) 高。 Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.
| Chinese alias | 4-[[[6-(环己基甲氧基)-7H-嘌呤-2-基]氨基]苯磺酰胺 | ||
| English alias | 4SP | 4eor | 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}benzene-1-sulfonamide | NCGC00346950-01 | HY-15569 | 4eok | 2c6o | MS-26859 | NU-6102; NU 6102 | SCHEMBL12589612 | 1h1s | 2iw9 | 6-Cyclohexylmethoxy-2-(4 -sulfamoylanilino)purine | 4-{[6-(cyclohex | ||
| CAS number | 444722-95-6 | molecular formula | C18H22N6O3S |
| molecular weight | 402.5 | Exact mass | - |
| PSA | 144 | logp | 3.2 |
| CAS | 444722-95-6 |
| UNII | X5J53DR704 |
| Wikidata | Q27096041 |
| ChEMBL ID | CHEMBL319467 |
| AIDS 编号 | 618348 |
| DrugBank ID | DB07126 |
| PubChem CID | 4566 |
| Nikkaji Number | J1.983.937K |
| Pharos Ligand ID | 638SD9A4LQWZ |
| DSSTox Substance ID | DTXSID70274438 |
| Metabolomics Workbench ID | 150310 |
| PubChem Reference Collection SID | 505851283 |
| XLogP3 | XLogP3-AA: 3.2 |
| 复杂性 | 601 |
| Exact Mass | 402.14740976 |
| 形式电荷 | 0 |
| 重原子计数 | 28 |
| Molecular Weight | 402.5 |
| Monoisotopic Mass | 402.14740976 |
| 可旋转键计数 | 6 |
| 氢键供体计数 | 3 |
| 氢键受体计数 | 8 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 144 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 0 |
| 未定义原子手性中心计数 | 0 |
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