YM-750 是一种有效的酰基:胆固醇酰基转移酶 (ACAT) 抑制剂 (IC50=0.18 μM)。ACAT催化胆固醇和长链脂肪酰辅酶A形成胆固醇酯。 YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC50=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A.
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YM 750
CAS number:138046-43-2 molecular formula:C31H36N2O
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Specs
| Chinese alias | N-环庚基-N-(9H-芴-2-基甲基)-N'-(2,4,6-三甲基苯基)脲 | ||
| English alias | HY-107396 | NCGC00371091-01 | Urea, N-cycloheptyl-N-(9H-fluoren-2-ylmethyl)-N'-(2,4,6-trimethylphenyl)- | MS-28238 | J-007090 | YM750 | YM-750 | YM 750 | AKOS024457396 | SCHEMBL4106190 | 1-cycloheptyl-1-(9H-fluoren-2-ylmethyl)-3-(2,4,6-trimethylphenyl)ure | ||
| CAS number | 138046-43-2 | molecular formula | C31H36N2O |
| molecular weight | 452.63 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 32.299 Ų | logp | 7.700 |
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