Omigapil maleate 是一种具有活性的 GAPDH 亚硝基化抑制剂,可消除 Aβ1-42 诱导的小鼠 tau 乙酰化,记忆障碍和运动功能障碍,Omigapil maleate 具有研究阿尔茨海默症的潜力。Omigapil maleate (CGP3446B maleate) 是一种有效的凋亡 (apoptosis) 抑制剂。Omigapil maleate 可用于研究先天性肌营养不良 (CMD)。 Omigapil maleate, a GAPDH nitrosylation inhibitor, abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate (CGP3446B maleate) is a apoptosis inhibitor. Omigapil maleate can be used for the research of congenital muscular dystrophy (CMD).
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CGP 3466B maleate
CAS number:200189-97-5 molecular formula:C19H17NO•C4H4O4
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compound introduction
Specs
| Chinese alias | N-(二苯[[b,f]氧杂环庚烷-10-基甲基)-N-甲基-N-(2-丙炔基)胺马来酸酯 | 奥米加匹马来酸盐 | CGP3466B 马来酸盐 | N-(二苯并[[b,f]氧杂环庚烷-10-基甲基)-N-甲基-N-(2-丙炔基)胺单马来酸盐 | Omigapil 马来酸盐 | ||
| English alias | Dibenzo(b,f)oxepin-10-ylmethyl-methyl-prop-2-ynyl-amine maleate | MLS006010781 | N-(Dibenz[b,f]oxepin-10-ylmethyl)-N-Methyl-N-(2-propynyl)amine maleate | N-(Dibenz(b,f)oxepin-10-ylmethyl)-N-methyl-N-(2-propynyl)amine monomaleic acid salt | N-(Dibenz[b,f]o | ||
| CAS number | 200189-97-5 | molecular formula | C19H17NO•C4H4O4 |
| molecular weight | 391.42 g/mol | Exact mass | ≥99%(HPLC) |
| PSA | 87.100 Ų | logp | - |
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