CAS number：2250019-92-0 molecular formula：C31H29ClN6O3S.HCl
Kira8 Hydrochloride (AMG-18 Hydrochloride) 是一种单选择性 IRE1α 抑制剂，可以变构减弱 IRE1α RNase 活性，IC50 为 5.9 nM。 Kira8 Hydrochloride (AMG-18 Hydrochloride) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
| Chinese alias | 2-氯-N-[6-甲基-5-[[3-[2-[(3S)-3-哌啶基氨基] -4-嘧啶基] -2-吡啶基]氧基] -1-萘]苯磺酰胺盐酸盐 | ||
| English alias | 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfonamide hydrochloride | ||
| CAS number | 2250019-92-0 | molecular formula | C31H29ClN6O3S.HCl |
| molecular weight | 637.58 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | - | logp | - |
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