LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40) , with EC 50 s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1 , is potential for the treatment of type 2 diabetes mellitus (T2DM) Form:Solid IC50& Target:EC50:7 nM (human GPR40), 1 nM (mouse GPR40), 3 nM (rat GPR40)
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LY2922470
CAS number:1423018-12-5 molecular formula:C28H29NO4S
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| Chinese alias | - | ||
| English alias | SCHEMBL14695980 | Benzenepropanoic acid, 4-[[5-[(3,4-dihydro-8-methoxy-1(2H)-quinolinyl)methyl]-2-thienyl]methoxy]-beta-1-propyn-1-yl-, (betaS)- | LY2922470 | LY-2922470 | MS-28826 | BDBM50204012 | 1423018-12-5 | (S)-3-(4-((5-((8-Methoxy-3,4-dihydroquinol | ||
| CAS number | 1423018-12-5 | molecular formula | C28H29NO4S |
| molecular weight | 475.60 g/mol | Exact mass | ≥99% |
| PSA | 87.200 Ų | logp | 5.500 |
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