compound introduction
NCT-502 is a human phosphoglycerate dehydrogenase ( PHGDH ) inhibitor, cytotoxic to PHGDH-dependent cancer cells, and reduces glucose-derived serine production, with an IC 50 of 3.7 μM against PHGDH In Vitro NCT-502 is cytotoxic to MDA-MB-468, with an EC 50 of 15.2 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 3.7 μM (PHGDH)
