SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer In Vivo SCD1 inhibitor-3 (compound 17a) (5 mg/kg; p.o.; 4 hours) reduces the plasma C16:1/C16:0 triglycerides desaturation index by 54 % . SCD1 inhibitor-3 (2~10 mg/kg; p.o.; 4 hours) makes a dose-responsive reduction of plasma triglycerides desaturation index . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Lewis rats Dosage: 5 mg/kg Administration: P.o.; 4 hours Result: Reduced the plasma C16:1/C16:0 triglycerides desaturation index by 54 %. Animal Model: Lewis rats Dosage: 2~10 mg/kg Administration: P.o.; 4 hours Result: A dose-responsive reduction of plasma triglycerides desaturation index. Form:Solid IC50& Target:SCD1
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SCD1 inhibitor-3
CAS number：1282606-48-7 molecular formula：C19H16FN7O2
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| Chinese alias | SCD1抑制剂-3 | ||
| English alias | - | ||
| CAS number | 1282606-48-7 | molecular formula | C19H16FN7O2 |
| molecular weight | 393.37 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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