AZD1940 is an orally active, high affinity cannabinoid CB1/CB2 receptor agonist with pK i values of 7.93 and 9.06 for human CB1R and CB2R , respectively. AZD1940 shows a robust analgesia action In Vitro AZD1940 binds with high affinity to human, rat and mouse CB1 and CB2 receptors and displays full agonism at both receptors in all three species . MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo When given orally to rats, AZD1940 produces a robust analgesia in different models of inflammatory and neuropathic pain. For AZD1940, low brain uptake at analgesic doses has been demonstrated in both rats and primates . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:hCB1-R 7.93 (pKi) hCB2-R 9.06 (pKi)
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AZD1940
CAS number：881413-29-2 molecular formula：C20H29F2N3O2S
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| Chinese alias | - | ||
| English alias | N-[1-[(4,4-Difluorocyclohexyl)methyl]-2-(1,1-dimethylethyl)-1H-benzimidazol-5-yl]ethanesulfonamide | AKOS040750671 | UNII-0J0035E9FT | BDBM50536919 | ART-2713 | HY-119104 | N-{2-tert-Butyl-1-[(4,4-difluorocyclohexyl)methyl]-1H-benzimidazol-5-yl}ethanesulf | ||
| CAS number | 881413-29-2 | molecular formula | C20H29F2N3O2S |
| molecular weight | 413.52 g/mol | Exact mass | ≥99% |
| PSA | 72.400 Ų | logp | 4.500 |
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