CAS number：24449-39-6 molecular formula：C30H26O4
Tectol, isolated from Lippia sidoides , exhibits significant activity against human leukemia cell lines HL60 and CEM Tectol is a farnesyltransferase (FTase) inhibitor with IC 50 s of 2.09 and 1.73 μM for human and T. brucei FTase, respectively. Tectol inhibits drug-resistant strain of P. falciparum (FcB1) with an IC 50 of 3.44 μM Form:Solid IC50& Target:Plasmodium
| Chinese alias | 泰克托尔 | ||
| English alias | 5-(6-hydroxy-2,2-dimethylbenzo[h]chromen-5-yl)-2,2-dimethylbenzo[h]chromen-6-ol | MS-28174 | AKOS030534862 | DTXSID30947318 | Tectol | 2,2,2',2'-Tetramethyl-2H,2'H-[5,5'-bibenzo[h]chromene]-6,6'-diol | HY-N7634 | (5,5'-Bi-2H-naphtho(1,2-b)pyran)-6,6'-diol | ||
| CAS number | 24449-39-6 | molecular formula | C30H26O4 |
| molecular weight | 450.53 g/mol | Exact mass | ≥98% |
| PSA | 58.900 Ų | logp | 7.200 |
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