compound introduction
CCMI (AVL-3288) 是一种有效、选择性的 α7 nAChR 正向别构调节剂，不是通过正性结合位点与 α7 nAChR 结合并使其激活，能有效正向调节 α7 nAChR 上激动剂诱导的电流。CCMI 在神经系统认知功能紊乱疾病中具有潜在疗效。
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CCMI
CAS number：917837-54-8 molecular formula：C19H15Cl2N3O2
overview
Specs
| Chinese alias | [N-(4-氯苯基)]-α-[(4-氯苯基)-氨基亚甲基] -3-甲基-5-异恶唑乙酰胺 | ||
| English alias | 5-Isoxazoleacetamide,N-(4-chlorophenyl)-a-[[(4-chlorophenyl)amino]methylene]-3-methyl- | (Z)-3-(4-Chloroanilino)-N-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide | AVL-3288 | SCHEMBL1459686 | UNII-VA80VAX4WF | AKOS040759132 | CCMI | UCI-4083 | A | ||
| CAS number | 917837-54-8 | molecular formula | C19H15Cl2N3O2 |
| molecular weight | 388.25 g/mol | Exact mass | ≥98% |
| PSA | 67.200 Ų | logp | 5.200 |
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