CAS number：1219927-22-6 molecular formula：C21H20ClF2N5OS
RO2959 monohydrochloride 是一种有效的选择性 CRAC 通道抑制剂，IC50 为 402 nM。RO2959 monohydrochloride 是由 Orai1/Stim1 通道介导的钙存储进入 (SOCE) 的有效阻滞剂，IC50 为 25 nM。RO2959 monohydrochloride 还是人 IL-2 产生的有效抑制剂，有效阻断 T 细胞受体触发的基因表达和 T 细胞功能途径。 Information RO2959 hydrochloride is a potent and selective inhibitor of CRAC channel with IC50 of 402 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2.
| Chinese alias | - | ||
| English alias | RO2959 HCl | ||
| CAS number | 1219927-22-6 | molecular formula | C21H20ClF2N5OS |
| molecular weight | 463.93 g/mol | Exact mass | - |
| PSA | 99.300 Ų | logp | - |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
