compound introduction
Galicaftor (ABBV-2222; GLPG-2222) 是一种有效的，具有口服活性的囊性纤维化跨膜电导调节剂 (CFTR) 校正剂，可用于囊性纤维化的研究 Information Galicaftor (ABBV-2222) Galicaftor (ABBV-2222, GLPG2222) is a potent corrector of CFTR for the treatment of Cystic Fibrosis (CF). Targets CFTR In vitro ABBV-2222/GLPG2222 exhibits potent in vitro functional activity in primary patient cells harboring F508del/F508del CFTR with an EC50 Cell Research(from reference) Cell lines：CFBE41o-F508del CFTR-HRP cells Concentrations：0 - 20 μM Incubation Time：18-24 h
