Ilaprazole (IY-81149),一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制 H+/K+-ATPase,在兔壁细胞制剂中的 IC50 为 6 μM。Ilaprazole 用于胃溃疡的研究。Ilaprazole 也是一种有效的T细胞起源蛋白激酶 (TOPK) 抑制剂。
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Ilaprazole
CAS number:172152-36-2 molecular formula:C19H18N4O2S
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Specs
| Chinese alias | - | ||
| English alias | s3666 | ILAPRAZOLE [WHO-DD] | DTXSID10870115 | 2-[(4-methoxy-3-methyl-pyridin-2-yl)methylsulfinyl]-6-pyrrol-1-yl-1h-benzoimidazole | GTPL10512 | 1H-Benzimidazole,2-[[(4-methoxy-3-methyl-2-pyridinyl)methyl]sulfinyl]-5-(1H-pyrrol-1-yl)- (9CI) | Ilaprazole [ | ||
| CAS number | 172152-36-2 | molecular formula | C19H18N4O2S |
| molecular weight | 366.44 g/mol | Exact mass | - |
| PSA | 92.000 Ų | logp | 2.3 |
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