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5-[(2-Methylphenyl)methoxy]-2-phenyl-1-benzofuran-3-carboxylic acid

CAS number:307552-53-0    molecular formula:C23H18O4

overview

compound introduction

SLC26A3-IN-1 是一种阴离子交换蛋白SLC26A3的抑制剂 (IC50=340 nM)。SLC26A3 属于溶质载体 (SLC) 蛋白,属于 SLC26 家族。SLC26 家族对氯化物、碳酸氢盐、硫酸盐和草酸盐具有广泛的阴离子特异性。SLC26A3 在腺瘤 (DRA) 中下调,参与氯化物和草酸盐的肠道吸收。SLC26A3 功能突变的丧失与氯离子丢失性腹泻有关。

Specs

Chinese alias-
English alias-
CAS number307552-53-0molecular formulaC23H18O4
molecular weight358.4 g/molExact mass-
PSA59.700 Ųlogp5.300

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