compound introduction
DC-SX029 是一种口服有效的SNX10蛋白质-蛋白质相互作用 (PPI) 抑制剂，通过表面等离子共振 (SPR) 实验获得KD约为 0.935 μM。DC-SX029 阻断 SNX10-PIKfyve 相互作用，从而减少 TBK1/c-Rel 信号传导激活。DC-SX029 不影响SNX10的蛋白水平。DC-SX029 具有用于炎症性肠病 (IBD) 研究的潜力。
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5,5,5-Trifluoro-4-({4-[(methoxycarbonyl)amino]benzenesulfonamido}methyl)pentanoic acid
CAS number：300713-88-6 molecular formula：C14H17F3N2O6S
overview
Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 300713-88-6 | molecular formula | C14H17F3N2O6S |
| molecular weight | 398.360 g/mol | Exact mass | ≥98% |
| PSA | 130.000 Ų | logp | 1.700 |
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