(R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC 50 of 3 nM. (R)-MLT-985 has an IC 50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells.
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(R)-MLT-985
CAS number:1832577-07-7 molecular formula:C17H15Cl2N9O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1832577-07-7 | molecular formula | C17H15Cl2N9O2 |
| molecular weight | 448.27 g/mol | Exact mass | - |
| PSA | - | logp | - |
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