ZM-306416(CB 676475)是VEGFR选择性抑制剂(IC50为670nM),对于Flk-1(KDR)和Flt的IC50分别为100nM和2μM。 ZM-306416(CB 676475) is a VEGFR inhibitor that inhibits Flk-1 (KDR) (IC50=100 nM) and Flt (IC50 =2 μM); displays 4-fold selectivity over FGFR-1; inhibitor of c-Abl, Flt-1 and Src
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ZM 306416
CAS number:690206-97-4 molecular formula:C16H13ClFN3O2
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| Chinese alias | - | ||
| English alias | s2897 | HY-13785 | KBio2_005169 | N-(4-Chloro-2-fluorophenyl)-6,7-dimethoxy-4-quinazolinamine | 1-[2-[(4-Chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole | C16H13ClFN3O2 | SB16593 | 4-Quinazolinamine,N-(4-chloro-2-fluorophenyl)-6,7-dimethox | ||
| CAS number | 690206-97-4 | molecular formula | C16H13ClFN3O2 |
| molecular weight | 333.74 g/mol | Exact mass | - |
| PSA | 56.300 Ų | logp | 4.100 |
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