compound introduction
O-去甲基吉非替尼是吉非替尼的主要代谢产物，它是EGFR中酪氨酸残基磷酸化的有效抑制剂。 O-Desmethyl Gefitinib is a major metabolite of Gefitinib, which is a potent inhibitor of tyrosine residue phosphorylation in EGFR.
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O-Desmethyl Gefitinib
CAS number：847949-49-9 molecular formula：C21H22ClFN4O3
overview
Specs
| Chinese alias | - | ||
| English alias | UNII-53LPA3P6SI | 4-[(3-Chloro-4-fluorophenyl)amino]-7-hydroxy-6-(3-morpholinopropoxy)quinazoline | BCP15109 | 53LPA3P6SI | Q27261113 | 4-[(3-CHLORO-4-FLUOROPHENYL)AMINO]-6-[3-(4-MORPHOLINYL)PROPOXY]-7-QUINAZOLINOL | 4-(3-chloro-4-fluoroanilino)-6-(3-morp | ||
| CAS number | 847949-49-9 | molecular formula | C21H22ClFN4O3 |
| molecular weight | 432.88 g/mol | Exact mass | ≥98% |
| PSA | 79.700 Ų | logp | 3.800 |
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