CAS number：186610-89-9 molecular formula：C20H19N3O2
SU 4984是成纤维细胞生长因子受体1（F1g）的酪氨酸激酶活性的抑制剂。SU 4984还抑制αFGF诱导的ERK1和ERK2的酪氨酸磷酸化以及PDGF受体和胰岛素受体的酪氨酸磷酸化。然而，它不抑制EGF受体的激酶活性。 SU 4984 is an inhibitor of tyrosine kinase activity of fibroblast growth factor receptor 1 (Flg). SU 4984 also inhibits αFGF-induced tyrosine phosphorylation of ERK1 and ERK2 and the tyrosine phosphorylation of the PDGF receptor and the insulin receptors. it does not, however, inhibit the kinase activity of the EGF receptor.
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 186610-89-9 | molecular formula | C20H19N3O2 |
| molecular weight | 333.4 | Exact mass | ≥98% |
| PSA | 52.7 | logp | 2.3 |
| CAS | 186610-89-9 |
| PubChem CID | 5306 |
| XLogP3 | XLogP3-AA: 2.3 |
| 复杂性 | 531 |
| Exact Mass | 333.147726857 |
| 形式电荷 | 0 |
| 重原子计数 | 25 |
| Molecular Weight | 333.4 |
| Monoisotopic Mass | 333.147726857 |
| 可旋转键计数 | 2 |
| 氢键供体计数 | 1 |
| 氢键受体计数 | 3 |
| 共价键单元计数 | 1 |
| 同位素原子计数 | 0 |
| 拓扑极性表面积 | 52.7 Ų |
| 定义键立体中心计数 | 0 |
| 定义原子立体中心计数 | 0 |
| 未定义键立体中心计数 | 1 |
| 未定义原子手性中心计数 | 0 |
No safety information yet
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