Indirubin Derivative E804, 是类胰岛素生长因子1型受体 (IGF1R) 的有效抑制剂,其 IC50 值为 0.65 μM。 Indirubin Derivative E804 is a potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM for IGF1R. Indirubin Derivative E804 is a water-soluble indirubin derivative as potent inhibitor of Insulin-like Growth Factor 1 Receptor (IGF1R), with an IC50 of 0.65 μM. Indirubin Derivative E804 also inhibits CDK2/CycE with an EC50 of 0.23 μM
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Indirubin Derivative E804
CAS number:854171-35-0 molecular formula:C20H19N3O4
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| Chinese alias | 靛玉红衍生物 E804 | ||
| English alias | Indirubin E804 | ||
| CAS number | 854171-35-0 | molecular formula | C20H19N3O4 |
| molecular weight | 365.38 g/mol | Exact mass | - |
| PSA | 110.000 Ų | logp | 2.400 |
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