CAS number：1402709-93-6 molecular formula：C22H23Cl2N7
Information CCT241736 is a potent and orally bioavailable dual inhibitor of FLT3 and Aurora kinase with Kd of 7.5 nM, 48 nM, 6.2 nM, 38 nM and 14 nM for Aurora-A, Aurora-B, FLT3 kinase, FLT3-ITD and FLT3(D835Y), respectively. CCT241736 inhibits Aurora-A with IC50 of 38 nM.
| Chinese alias | - | ||
| English alias | BCP29563 | MS-28315 | 6-Chloro-7-(4-(4-chlorobenzyl)piperazin-1-yl)-2-(1,3-dimethyl-1H-pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine | UNII-ZE94SP78UG | BDBM50401421 | ZE94SP78UG | 6-Chloro-7-[4-(4-chlorobenzyl)-1-piperazinyl]-2-(1,3-dimethyl-4-pyrazolyl)-3H-im | ||
| CAS number | 1402709-93-6 | molecular formula | C22H23Cl2N7 |
| molecular weight | 456.4 g/mol | Exact mass | - |
| PSA | 65.900 Ų | logp | 3.800 |
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