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Gusacitinib

CAS number：1425381-60-7    molecular formula：C24H28N8O2

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overview

compound introduction

Information Gusacitinib (ASN-002) is an orally active and potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 of 5-46 nM. Gusacitinib has anti-cancer activity.

Specs

Chinese alias-
English alias1-(4-(4-(4-Hydroxy-piperidin-1-yl)-phenylamino)-5-oxo-5,6-dihydro-pyrimido(4,5-D)pyridazin-2-yl)-piperidin-4-YL-acetonitrile | AKOS040741172 | example 189 [WO2013028818A1] | Gusacitinib [INN] | GTPL10000 | MS-28452 | UNII-4801QYW816 | Gusacitinib [USAN] |
CAS number1425381-60-7molecular formulaC24H28N8O2
molecular weight460.53 g/molExact mass-
PSA130.000 Ųlogp2.6

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