CAS number：1660963-42-7 molecular formula：C29H28F2N6O2
Olafertinib 是三代 EGFR 酪氨酸酶抑制剂，其GI50 值分别为5 nM (EGFR L858R/T790M)、10 nM (EGFR del19) 和 689 nM (EGFR WT)。 Olafertinib is a third-generation EGFR TKI, with GI50 values of 5 nM (EGFR L858R/T790M), 10 nM (EGFR del19) and 689 nM (EGFR WT), respectively. Olafertinib has the potential for NSCLC research.
| Chinese alias | 奥拉替尼 (RX-518) | ||
| English alias | AKOS030632731 | olafertinib | N-[3-[2-[[2,3-difluoro-4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl]amino]quinazolin-8-yl]phenyl]acrylamide | 1660963-42-7 | IDRGFNPZDVBSSE-UHFFFAOYSA-N | AC-35884 | MFCD30345533 | C37H48N6O5S2 | EGFR-IN-3 | 2-Propenamide, N-[3 | ||
| CAS number | 1660963-42-7 | molecular formula | C29H28F2N6O2 |
| molecular weight | 530.57 g/mol | Exact mass | - |
| PSA | 93.600 Ų | logp | 4.300 |
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