LDN-192960 hydrochloride is an inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC 50 s of 10 nM and 48 nM, respectively In Vitro LDN-192960 hydrochloride (10 μM) is selective and inhibits ten of the other kinases by ≥90%, with only five being potently inhibited (IC 50 Form:Solid IC50& Target:IC50: 10 nM (Haspin),48 nM (DYRK2)
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LDN-192960 hydrochloride
CAS number:2309172-48-1 molecular formula:C18H22Cl2N2O2S
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| Chinese alias | LDN-192960 盐酸盐 | ||
| English alias | - | ||
| CAS number | 2309172-48-1 | molecular formula | C18H22Cl2N2O2S |
| molecular weight | 401.35 g/mol | Exact mass | ≥99% |
| PSA | 82.700 Ų | logp | - |
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