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Erlotinib D6

CAS number:1034651-23-4    molecular formula:C22H23N3O4

overview

compound introduction

Erlotinib-d6是 Erlotinib (CP-358774) 的氘代物。Erlotinib 是一种直接作用的EGFR酪氨酸激酶抑制剂,对人EGFR的 IC50为 2 nM。Erlotinib-d6 是一种点击化学试剂。它含有 Alkyne 基团,可以和含有 Azide 基团的分子发生铜催化的叠氮-炔环加成反应 (CuAAc)。

Specs

Chinese alias-
English alias-
CAS number1034651-23-4molecular formulaC22H23N3O4
molecular weight399.5 g/molExact mass-
PSA74.700 Ųlogp3.300

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