淀粉样物质是一种无固定形状的细胞外嗜酸性物质,可存在于不同的组织、器官导致的疾病称为淀粉样变。淀粉样物质主要是由蛋白质构成,该蛋白大部分排列成反向的β-折叠层结构。在电子显微镜下,淀粉样物质呈原纤维排列,病例材料中为大量细胞外的、不分支的细丝,大多随机排列。用于识别淀粉样物质的组织学方法有甲紫染色、刚果红染色、偏振光显微镜观察等。目前研究发现传统的甲紫染色法灵敏度低、特异性差,经典的而且有效的方法是刚果红染色,1922 年 Bennhold 发现了刚果红可以用于活体内淀粉样物质的鉴别,并应用到组织切片,后来经过Highman 改良,染色效果更好。 淀粉样物质染色液(改良 Stores 刚果红法),主要由 Stores 刚果红染色液和苏木素染 色液组成,碱性刚果红染色无分化步骤,但保存时间较短。 组分表 S774555
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Amyloid Staining Solution (Modified Stores Congo Red Method)
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | BioReagent |
| PSA | - | logp | - |
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