Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
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Recombinant Bovine CD64 Protein
CAS number：unknown molecular formula：
overview
compound introduction
Specs
| Chinese alias | 重组牛CD64蛋白 | 重组牛CD64蛋白 | ||
| English alias | CD64 antigen | CD64 | CD64a | Fc fragment of IgG, high affinity Ia, receptor (CD64) | Fc gamma RI | FCG1 | Fc-gamma receptor I B2 | Fc-gamma RI | Fc-gamma RIA | FcgammaRIa | FcgRI | FCGR1 | FcgRIA | FCRI | FcRIA | FLJ18345 | high affinity Ia, receptor for | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | 无动物源 |
| PSA | - | logp | - |
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