compound introduction
EPZ004777是一种有效的，选择性的DOT1L抑制剂，无细胞试验中IC50为0.4 nM。
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EPZ 004777
CAS number：1338466-77-5 molecular formula：C28H41N7O4
overview
Specs
| Chinese alias | 7-[5-脱氧-5-[[3-[[[[4-(1,1-二甲基乙基)苯基]氨基]羰基]氨基]丙基](1-甲基乙基)氨基]-β-D-呋喃呋喃糖基] -7H-吡咯并[2,3-d]嘧啶-4-胺 | ||
| English alias | EPZ004777 | 1338466-77-5 | 1-(3-((((2R,3S,4R,5R)-5-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea | EPZ 004777 | CHEMBL2169919 | 7-{5-[(3-{[(4-Tert-Butylphenyl)carba | ||
| CAS number | 1338466-77-5 | molecular formula | C28H41N7O4 |
| molecular weight | 539.67 g/mol | Exact mass | - |
| PSA | 151.000 Ų | logp | 2.400 |
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