4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity. In Vitro 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC 50 =4.2 μM) and W2 (IC 50 =4.8 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo 4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T 1/2 of 1.94 hours, a C max of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid
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4'-Hydroxy-2,4-dimethoxychalcone
CAS number:151135-64-7 molecular formula:C17H16O4
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| Chinese alias | 4'-羟基-2,4-二甲氧基查耳酮 | ||
| English alias | - | ||
| CAS number | 151135-64-7 | molecular formula | C17H16O4 |
| molecular weight | 284.31 g/mol | Exact mass | ≥99% |
| PSA | 55.800 Ų | logp | 3.300 |
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