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4'-Hydroxy-2,4-dimethoxychalcone

CAS number:151135-64-7    molecular formula:C17H16O4

overview

compound introduction

4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity. In Vitro 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC 50 =4.2 μM) and W2 (IC 50 =4.8 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo 4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T 1/2 of 1.94 hours, a C max of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Specs

Chinese alias4'-羟基-2,4-二甲氧基查耳酮
English alias-
CAS number151135-64-7molecular formulaC17H16O4
molecular weight284.31 g/molExact mass≥99%
PSA55.800 Ųlogp3.300

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