MMV008138 是一种选择性 2-C-甲基-d-赤藓糖醇4-磷酸胞苷酰转移酶(IspD)靶向抗疟药, 对PfIspD(P. falciparumIspD) 作用的IC50值为 44 nM。MMV008138 抑制对恶性疟原虫 Dd2 虫株生长的 IC50值为 250 nM。
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(1R,3S)-1-(2,4-dichlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
CAS number:1679333-73-3 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1679333-73-3 | molecular formula | |
| molecular weight | 361.200 g/mol | Exact mass | ≥99% |
| PSA | 65.099 Ų | logp | 1.800 |
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