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5-(Morpholin-4-yl)-8-(piperazin-1-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinoline

CAS number：372495-52-8    molecular formula：C20H25N7OS

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overview

compound introduction

UNC10201652 是一种有效的 L1 特异性肠道细菌 β-葡萄糖醛酸酶 (GUSs) 抑制剂，对大肠杆菌 (E. coli) 的IC50为 0.117 μM。UNC10201652 仅在粪便肠道菌群 L1 GUS 酶高度丰富的个体中才能阻断SN-38 glucuronide 的加工。

Specs

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CAS number372495-52-8molecular formulaC20H25N7OS
molecular weight411.500 g/molExact mass≥99%
PSA108.000 Ųlogp2.300

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