AZD6482是一种PI3Kβ抑制剂,IC50为10 nM,作用于PI3Kβ比作用于PI3Kδ, PI3Kα和PI3Kγ选择性分别高8,87和109倍。 AZD6482 is a PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ. A PI3K inhibitor and antiplatelet agent.
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AZD6482
CAS number:1173900-33-8 molecular formula:C22H24N4O4
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| Chinese alias | - | ||
| English alias | 2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid | HY-10344 | 2-({(1R)-1-[7-Methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid | InChI=1/C7H15N/c1-8-7-5-3-2-4-6-7/h7- | ||
| CAS number | 1173900-33-8 | molecular formula | C22H24N4O4 |
| molecular weight | 408.45 g/mol | Exact mass | - |
| PSA | 94.500 Ų | logp | 2 |
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