NVP-BGT226(BGT 226)是PI3K I型抑制剂,对PI3Kα/β/γ的IC50分别为4 nM/63 nM/38 nM。A novel dual PI3K/FRAP inhibitor BGT226 (NVP-BGT226) is a novel class I PI3K/mTOR inhibitor for PI3Kα/β/γ with IC50 of 4 nM/63 nM/38 nM. A novel dual PI3K/FRAP inhibitor
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BGT226 (NVP-BGT226) maleate
CAS number:1245537-68-1 molecular formula:C28H25F3N6O2.C4H4O4
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| Chinese alias | BGT226 (NVP-BGT226) 马来酸盐 | ||
| English alias | SCHEMBL996046 | BGT226 maleate | BGT-226 maleate | BGT226 (NVP-BGT226) | Di-2-thienyl ketone; Bis(2-thienyl)ketone~Di-2-thienyl ketone; dithiophen-2-ylmethanone;Di(thiophen-2-yl)methanone | NCGC00246927-01 | 1-(3-(Trifluoromethyl)-4-(piperazin-1-yl)phenyl | ||
| CAS number | 1245537-68-1 | molecular formula | C28H25F3N6O2.C4H4O4 |
| molecular weight | 650.6 g/mol | Exact mass | ≥98% |
| PSA | 148.000 Ų | logp | - |
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