Veliparib dihydrochloride是有效的 PARP1 和 PARP2 抑制剂,Ki 分别为5.2 nM,2.9 nM。 Veliparib (dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Kis of 5.2 nM and 2.9 nM in cell-free assays, respectively.
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Veliparib dihydrochloride
CAS number:912445-05-7 molecular formula:C13H16N4O•2HCl
overview
compound introduction
Specs
| Chinese alias | 2-[((2R)-2-甲基-2-吡咯烷基] -1H-苯并咪唑-4-羧酰胺二盐酸盐 | 维利帕尼二盐酸盐 | ||
| English alias | SCHEMBL2368883 | Veliparib dihydrochloride | HMS3295I11 | SB16479 | SCHEMBL19328639 | Veliparib hydrochloride | AS-17023 | 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide--hydrogen chloride (1/2) | AMY24139 | J-505212 | 2-[(2R)-2-methylpyr | ||
| CAS number | 912445-05-7 | molecular formula | C13H16N4O•2HCl |
| molecular weight | 317.21 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 83.800 Ų | logp | - |
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