组织蛋白酶B,人肝

组织蛋白酶B是一种半胱氨酸蛋白酶，位于溶酶体中，参与组织降解和重组。具体而言，组织蛋白酶B被认为参与内吞作用吸收的细胞外蛋白质的细胞内消化。 Cathepsin B, a cysteine proteinase, is located in lysosomes and is involved in tissue degradation and restructuring. Specifically, cathepsin B is believed to be involved in the intracellular digestion of extracellular proteins taken up by endocytosis. Ref: Rich D.H., Brown M.A. and Barrett A.J. 1986 Biochem J, 235, 731-734. Product Citations: Armstrong, Andrea, Niklas Mattsson, Hanna Appelqvist, Camilla Janefjord, Linnea Sandin, Lotta Agholme, Bob Olsson et al. "Lysosomal Network Proteins as Potential Novel CSF Biomarkers for Alzheimer’s Disease."Neuromolecular medicine 16, no. 1 (2014): 150-160. Watson, Andre, Cara Yocum, Vaibhav Pandit, and Shiva P. Kotha. "Optimizing Polymeric Nanoparticle Core Designs for Gene Delivery." In Bioengineering Conference (NEBEC), 2013 39th Annual Northeast, pp. 1-2. IEEE, 2013. Toneff, Thomas, Lydiane Funkelstein, Charles Mosier, Armen Abagyan, Michael Ziegler, and Vivian Hook. "Beta-Amyloid Peptides Undergo Regulated Co-Secretion with Neuropeptide and Catecholamine Neurotransmitters."Peptides (2013). Elie, Benelita Tina, Vasilena Gocheva, Tanaya Shree, Stacie A. Dalrymple, Leslie J. Holsinger, and Johanna A. Joyce. "Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model." Biochimie 92, no. 11 (2010): 1618-1624.

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