S29434 (NMDPEF) 是一种有效、竞争性、选择性、可透过细胞膜的醌还原酶 2 (quinone reductase 2 (QR2)) 抑制剂,在不同的组织层面,对人 QR2 的IC50值为 5-16 nM,对其选择性高于 QR1。S29434 (NMDPEF) 可诱导自噬,抑制 QR2 介导的 ROS 的产生。
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Nmdpef
CAS number:874484-20-5 molecular formula:C21H18N4O3
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 874484-20-5 | molecular formula | C21H18N4O3 |
| molecular weight | 374.4 g/mol | Exact mass | ≥99% |
| PSA | 82.200 Ų | logp | 2.300 |
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