AMG-208是c-Met抑制剂,IC50为9.3 nM。A highly selective Met inhibitor (IC50 = 9.3 nM) AMG-208 is a potent small molecular c-Met inhibitor with an IC50 of 9.3 nM. A highly selective Met inhibitor (IC50 = 9.3 nM)
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AMG-208
CAS number:1002304-34-8 molecular formula:C22H17N5O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | 1-Propanone,1-(2,4,6-trihydroxyphenyl)- | 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline | 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline | 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin | ||
| CAS number | 1002304-34-8 | molecular formula | C22H17N5O2 |
| molecular weight | 383.41 g/mol | Exact mass | ≥98% |
| PSA | 74.400 Ų | logp | 3.1 |
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