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1-Methyladenosine

CAS number:15763-06-1    molecular formula:C11H15N5O4

overview

compound introduction

1-Methyladenosine 是一种 RNA 修饰,可作为肿瘤标志物,其体内水平升高与癌症发生有关。1-Methyladenosine 甲基化后可通过上调 PPARδ 表达,调节胆固醇代谢并激活 Hedgehog 信号通路,来驱动肝脏肿瘤的发生。 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.

Specs

Chinese alias-
English aliasH10051 | AC-32347 | Adenosine, N,6-didehydro-1,9-dihydro-1-methyl- | HY-113081 | (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diol | NCGC00163305-01 | Adenosine, 1-methyl- | AKOS030241121 | PD018070 | Q161643 |
CAS number15763-06-1molecular formulaC11H15N5O4
molecular weight281.27 g/molExact mass≥98%
PSA127.000 Ųlogp-1.000

numbering system

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physicochemical properties

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Production methods and uses

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Related

upstream information

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downstream information

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MSDS

Found 1 shareMSDS
15763-06-1 | 1-Methyladenosine | 1-Methyladenosine