CAS number：146062-49-9 molecular formula：C19H18N2O4S
MSDC 0160 (Mitoglitazone) 是调节噻唑烷二酮的线粒体靶标 (mTOT) 的胰岛素增敏剂，也是线粒体丙酮酸载体 (MPC) 的调节剂。MSDC 0160 是一种噻唑烷二酮 (TZD)，具有抗糖尿病和神经保护活性作用。MSDC 0160 具有用于阿尔茨海默氏病的潜力。 MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimer′s disease.
| Chinese alias | - | ||
| English alias | CHEBI:94409 | U-91325 | US9562012, mitoglitazone | 5-[[4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione | CAY10415(MSDC-0160) | 5-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)-benzyl)thiazolidine-2,4-dione | 5-(4-(2-(5-ethylpyri | ||
| CAS number | 146062-49-9 | molecular formula | C19H18N2O4S |
| molecular weight | 370.42 g/mol | Exact mass | - |
| PSA | 111.000 Ų | logp | 3.500 |
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