Aladdin™ Amine-PEG4-Desthiobiotin

Product introduction： Amine-PEG4-Desthiobiotin is a pegylated amine compound whose biotin-like group is elutable from streptavidin, making it ideal for carbodiimide (EDC) conjugation to carboxylates for labeling and purification. Features of EZ-Link Amine-PEG4-Desthiobiotin, No-Weigh Format: • Desthiobiotin —analog of biotin allows easy elution from streptavidin, an ideal feature for affinity purification applications • Amine-activated —primary amine can be crosslinked to proteins and material surfaces using EDC and other crosslinkers • Pegylated —polyethylene glycol (PEG) groups in spacer arm enhances water solubility of biotinylated molecules This desthiobiotin compound is an amine-modified analog of biotin that contains a 4-unit polyethylene glycol (PEG) spacer arm. Desthiobiotinylation is accomplished by conjugating the primary amine to carboxyl groups on surface materials, peptides or proteins using the carbodiimide crosslinker . Carboxyl groups (-COOH) occur in aspartate or glutamate residues and the carboxy-terminus of polypeptides. When activated with NHS-ester Chemistry). • Spacer: Pegylated,28.8 Å • Labeling Method: Chemical Labeling • Cell Permeability: Cell-Impermeant

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