Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Non-cleavable
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Maleimide-DOTA
CAS number:1006711-90-5 molecular formula:C22H34N6O9
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compound introduction
Specs
| Chinese alias | 马来酰亚胺-DOTA | ||
| English alias | PD171104 | 2-[4,7-bis(carboxymethyl)-10-[2-[2-(2,5-dioxopyrrol-1-yl)ethylamino]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid | Maleimide-monoamide-DOTA | 1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide | 1,4,7,1 | ||
| CAS number | 1006711-90-5 | molecular formula | C22H34N6O9 |
| molecular weight | 526.54 g/mol | Exact mass | ≥99% |
| PSA | 191.000 Ų | logp | -9.300 |
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