Description This heterobifunctional, PEGylated crosslinker 17-Azido-3,6,9,12,15-pentaoxaheptadecanoic acid features a carboxyl group at one end and azide at the other. The hydrophillic PEG linker facilitates solubility in biological applications. This azido-PEG5-acid linker can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC®molecules) fortargeted protein degradation.
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Azido-PEG5-CH2CO2H
CAS number:217180-81-9 molecular formula:C12H23N3O7
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Specs
| Chinese alias | 17-叠氮基-3,6,9,12,15-五氧杂十七烷酸 | ||
| English alias | Azido-PEG5-acid | ||
| CAS number | 217180-81-9 | molecular formula | C12H23N3O7 |
| molecular weight | 321.33 g/mol | Exact mass | ≥95% |
| PSA | 97.800 Ų | logp | 0.000 |
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