DBCO-Sulfo-Link-biotin 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联活性分子 (ADCs) 的合成。DBCO-Sulfo-Link-biotin 是一种点击化学试剂。它含有 DBCO 基团，可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。 DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Sulfo-Link-biotin is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-Sulfo-Link-biotin is a biotinylated reagent useful for introducing a biotin moiety to proteins and cell surfaces containing azide moiety using copper-free Click Chemistry. This biotin compound is membrane-impermeable due to its negatively charged, water soluble sulfonate group. DBCO is commonly used for copper-free Click Chemistry reactions.
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DBCO-Sulfo-Link-biotin
CAS number：1363444-70-5 molecular formula：C31H35N5O7S2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1363444-70-5 | molecular formula | C31H35N5O7S2 |
| molecular weight | 653.77 g/mol | Exact mass | ≥95% |
| PSA | 208.000 Ų | logp | 0.900 |
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