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N3-Ph-NHS ester

CAS number:53053-08-0    molecular formula:C11H8N4O4

overview

compound introduction

N-Hydroxysuccinimidyl-4-azidobenzoate is an aryl azide-based, amine- and photoreactive crosslinker. Product description: N3-Ph-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N3-Ph-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Specs

Chinese aliasN-羟基琥珀酰亚胺基4-叠氮苯甲酸酯 | 4-叠氮苯甲酸 N-琥珀酰亚胺基酯 | 4-叠氮苯甲酸 N-羟基琥珀酰亚胺基酯 | 4-叠氮苯甲酸2,5-二氧代吡咯烷-1-基酯 | 1-[(4-叠氮苯甲酰基)氧基]-2,5-吡咯烷二酮
English aliasYSZCJ045 | 4-Azidobenzoic acid N-hydroxysuccinimide ester | n-(4-azidobenzoyloxy)succinimide | HY-126524 | 4-Azidobenzoyloxysuccinimide | N-HYDROXYSUCCINIMIDE 4-AZIDOBENZOIC ESTER | 2,5-DIOXOPYRROLIDIN-1-YL 4-AZIDOBENZOATE | 3-hydroxy-2,5-dioxopyrrolidin-
CAS number53053-08-0molecular formulaC11H8N4O4
molecular weight260.21 g/molExact mass≥98%
PSA78.000 Ųlogp1.800

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