Application SR 16832 is a dual site PPARγ inhibitor. Acts at orthosteric and allosteric sites in the ligand binding domain. Inhibits binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonists.
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SR 16832
CAS number:2088135-12-8 molecular formula:C17H12ClN3O4
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| Chinese alias | 2-氯-N-(6-甲氧基-4-喹啉基)-5-硝基苯甲酰胺 | ||
| English alias | 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide | 2-Chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide | ||
| CAS number | 2088135-12-8 | molecular formula | C17H12ClN3O4 |
| molecular weight | 357.75 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 97.000 Ų | logp | 3.500 |
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