CAS number：180713-37-5 molecular formula：C26H36O3
产品应用： LG100754 (UVI 2112) 是一种 RXR 二聚体 的调节剂。LG100754 作为同源二聚体 RXR:RXR 的拮抗剂，但作为异源二聚体 RXR: PPARα 和 RXR: PPARγ 的激动剂。LG100754 是一种通过 RXR 起作用的胰岛素增敏剂。 Application: LG100754 (UVI 2112) is a modulator of RXR dimers. LG100754 acts as an antagonist of the homodimeric RXR:RXR, but as an agonist of the heterodimeric RXR:PPARα and RXR:PPARγ. LG100754 is an insulin sensitizer acting through RXR.
| Chinese alias | - | ||
| English alias | LGD 100754 | LG 100754 | (2E,4E,6Z)-3-Methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydro-naphthalen-2-yl)-octa-2,4,6-trienoic acid | (2e,4e,6z)-3-Methyl-7-(5,5,8,8-Tetramethyl-3-Propoxy-5,6,7,8-Tetrahydronaphthalen-2-Yl)octa-2,4,6-Trienoic Acid | | ||
| CAS number | 180713-37-5 | molecular formula | C26H36O3 |
| molecular weight | 396.56 g/mol | Exact mass | - |
| PSA | 46.500 Ų | logp | 8.400 |
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