Heclin 是一种 HECT E3 泛素连接酶抑制剂。Heclin 抑制组织培养细胞中的几种 HECT 连接酶(对于 Smurf2、Nedd4 和 WWP1 HECT 连接酶结构域的IC50s 分别为 6.8、6.3 和 6.9 μM)。
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Heclin
CAS number:890605-54-6 molecular formula:C17H17NO3
overview
compound introduction
Specs
| Chinese alias | N-(4-乙酰基苯基)-3-(5-乙基-2-呋喃基)-2-丙烯酰胺 | ||
| English alias | N-(4-Acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide | ||
| CAS number | 890605-54-6 | molecular formula | C17H17NO3 |
| molecular weight | 283.32 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 59.300 Ų | logp | 2.800 |
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