compound introduction
Mito-TEMPO是针对线粒体的抗氧化剂，有助于防止对线粒体的氧化损伤。它具有超氧化物和烷基自由基清除性能。研究表明，Mito-TEMPO促进线粒体中促凋亡蛋白的释放，减弱ATP耗竭恢复介导的坏死和细胞凋亡。已显示有助于阻止对心肌细胞心脏Na | + |通道的负面影响。 Mito-TEMPO is a mitochondria-targeted antioxidant that helps protect against oxidative damage to the mitochondria. It has superoxide and alkyl radical scavenging properties. Mito-TEMPO has been shown to facilitate in the release of proapoptotic proteins from the mitochondria, attenuating ATP-depletion recovery-mediated necrosis and apoptosis. It has been shown to help block negative effects on the cardiac Na|+|channel in cardiomyocytes.
