苯那普利拉是贝那普利的活性代谢产物，在酯基裂解后形成。贝那普利拉是血管紧张素转换酶（ACE）的有效抑制剂。这防止了血管紧张素I转化为血管收缩血管紧张素II。 Benazeprilat 是一种具有活性的贝那普利活性代谢物，贝那普利是一种具有抗高血压活性的含羧基血管紧张素转换酶 ACE 抑制剂。Benazeprilat 是一种公认的抗高血压剂，无论是单药研究还是与其他类别的药物（包括噻嗪类利尿剂和钙通道阻滞剂）联合使用。Benazeprilat 是减少与心血管风险和继发性终末器官损伤相关的各种病理的一线研究药物。 Benazeprilat is the active metabolite of benazepril , formed after cleavage of the ester group. Benazeprilat is a potent inhibitor of angiotensin-converting enzyme (ACE). This prevents the conversion of angiotensin I to the vasoconstrictor angiotensin II. Product description Benazeprilat is an active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage.
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Benazeprilat
CAS number：86541-78-8 molecular formula：C22H24N2O5
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid | CGS 14831 | ||
| CAS number | 86541-78-8 | molecular formula | C22H24N2O5 |
| molecular weight | 396.44 g/mol | Exact mass | - |
| PSA | 107.000 Ų | logp | 0.600 |
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86541-78-8 | Benazepril Related Compound C.pdf
